In a breakthrough discovery, researchers from the University of Regensburg have developed a novel method for synthesizing complex molecules without the need for organic solvents or other additives. By applying the molecules to a water surface and irradiating them with violet light, a thin film is formed where the molecules react to form the desired product. This innovative approach takes advantage of the film formation of water-insoluble organic molecules on the water surface, providing ideal conditions for activation by light.

One of the key advantages of this new methodology is its environmental friendliness. Traditional synthesis reactions often involve the use of organic solvents, metal catalysts, and reagents that can generate waste and have a negative impact on the environment. By eliminating the need for these additives, the production of chemical products becomes more efficient and sustainable. The results of this research have been published in Science, highlighting the significance of this new approach in the field of chemistry.

The breadth of application of this technology has been demonstrated through more than 160 examples, including the synthesis of precursors of drugs. With the ability to carry out the synthesis in a flow reactor, larger amounts of product can be produced continuously. Spectroscopic measurements have provided insight into the molecular mechanism of the reaction, paving the way for further developments and applications. The researchers are now focusing on applying this synthesis technology to other reactions to expand its potential in the production of chemical products.

As the project continues to evolve, the researchers are optimistic about the wide range of applications that this green approach to chemical synthesis can achieve. By eliminating the need for organic solvents and other additives, the production of complex molecules can be more sustainable and environmentally friendly. The success of this research opens up new possibilities for the future of chemical synthesis and paves the way for a greener approach to manufacturing chemical products.


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