The search for effective treatments for long COVID has been ongoing, with researchers exploring various avenues to provide relief for individuals suffering from debilitating symptoms. Recently, a case study highlighted the remarkable improvement in long COVID symptoms experienced by a 41-year-old woman after using psychedelics such as MDMA and psilocybin under the guidance of a therapist.

The patient, who was previously healthy before contracting COVID-19, tried traditional methods such as fasting, massage therapy, and meditation to alleviate her symptoms of fatigue, anxiety, depression, joint pain, and headaches. However, these methods only offered temporary relief or no improvement at all. After facing challenges in accessing a long COVID clinic, the patient turned to psychedelics for relief.

In May 2022, the woman consumed a gram of ‘golden teacher’ Psilocybe cubensis mushrooms, followed by 125 milligrams of MDMA and subsequent doses of psilocybin. The results were significant, with the patient reporting an 80 percent improvement in her overall symptoms. She described feeling detached from her long COVID symptoms, with a sense of being in a childlike state and a strong connection to nature.

Over the following months, the woman continued to experience minor setbacks but ultimately reported the complete resolution of her symptoms by the end of 2022. She was able to resume her PhD studies and return to full-time work. The use of psychedelics in this case study suggests a potential link between the brain-altering effects of these substances and the alleviation of long COVID symptoms, particularly brain fog.

It is essential to note that this case study is based on a single individual without randomization, a control group, or dosage control. While other anecdotal reports also suggest the potential benefits of psychedelics for long COVID, further scientific research is necessary to determine the efficacy and safety of using these substances as a form of treatment. Columbia University has initiated a small pilot trial to investigate the impact of hallucinogenic treatments on long COVID symptoms.

The case study of the 41-year-old woman highlights the potential of psychedelics such as MDMA and psilocybin in providing relief for long COVID symptoms. While the results are promising, it is crucial to approach these findings with caution and await more comprehensive research to validate the effectiveness of psychedelics as a treatment for long COVID. In the meantime, individuals struggling with long COVID should consult healthcare professionals for evidence-based treatment options.


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